The aim of the experiment was to investigate the effect of semen carthamus tinctorius Laqua-acupuncture on the total bone mineral density(BND) and the trabecular area of proximal tibia in ovariectomized osteoporotic rats.
The results were as follows:
1. In total bone mineral density(BND), Control group(ovariectomized and saline aqua-acupuncture) were decreased 3.2% compare to that before the experiment. Estrogen group(ovariectomized and estrogen injection) were increased 2.9% compare to that before the experiment. Exp I. II. III group(semen carthamus tinctorius L. aqua-acupuncture, repectively 5㎕, 50㎕, 150㎕) were respectively decreased 0.8%, 1.4%, 0.5% compare to that before experiment.
2. In trabecular area in epiphysis of proximal tibia, Control group were decreased 1.7% compared to that in sham group(sham operated and saline aqua-acupuncture). Estrogen group were significantly increased 3.5% (P<0.005) compared to that in control group. Exp. I. II. III groups were significantly increased respectively 5.8%, 5.4%, 4.1% (P<0.05) compared to that in control group.
3. In trabecular area in diaphysis of proximal tibia, Control group were signifieantly decreased 12.9% compared to that in sham group(P<0.05). Estrogen group were significantly increased 14.7%(P<0.05) compared to that in control group. Exp I. II. III groups were significantly increased respectively 11.9%, 6.5%, 10.5%, (P<0.0005, P<0.005, P<0.0005) compared to that in control group.
From the above results, It suggested that semen carthamus tinctorius L aqua-acupncture can be used to decrease in bone turnover and increase in bone mass in osteoporotic rats induced by ovariectomy.
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